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目的探讨新诊断2型糖尿病(T2DM)患者血液流变学特点。方法在某医院2009年1月-2010年12月的体检人群中,根据1999年WHO的糖尿病诊断标准选择新诊断的T2DM患者80例作为T2DM组;选择100例健康者作为对照组,检测两组血液流变学及相关生化指标并进行统计学分析。结果新诊断T2DM患者的空腹血糖(FPG)、总胆固醇(TC)、甘油三酯(TG)、尿酸(UA)均高于对照组,差异有统计学意义(P<0.05);血液流变检测指标全血黏度、血浆黏度、血沉方程K值、红细胞压积及纤维蛋白原均高于对照组,差异有统计学意义(P<0.05)。结论新诊断T2DM患者存在血液流变学的改变,表现为高黏血症。
Objective To investigate the hemorheological characteristics of newly diagnosed type 2 diabetes mellitus (T2DM). Methods Totally 80 newly diagnosed T2DM patients were selected as the T2DM group from January 2009 to December 2010 in a hospital based on the diagnostic criteria of WHO in 1999. 100 healthy controls were selected as the control group, Hemorheology and related biochemical indicators and statistical analysis. Results Fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), and uric acid (UA) in newly diagnosed T2DM patients were significantly higher than those in control group (P <0.05) Index of whole blood viscosity, plasma viscosity, erythrocyte sedimentation rate K value, hematocrit and fibrinogen were higher than the control group, the difference was statistically significant (P <0.05). Conclusion There is a hemorheological change in newly diagnosed T2DM patients, which is hyperviscosity.