探讨黄芩的致突变性。以 ３种剂量（１０ ｇ／ｋｇ、２０ ｇ／ｋｇ、３０ ｇ／ｋｇ）的黄芩作为实验组；以同体积生理盐水（ＮＳ）作为阴性对照组；以 ３０ ｍｇ／ｋｇ的环磷酰胺（ＣＰ）作为阳性对照组。以母鼠胸骨骨髓与胎鼠肝脏血作微核分析，以小鼠血淋巴细胞作单细胞凝胶电泳（ＳＣＧＥ）试验。结果与阴性对照组相比，黄芩各剂量组各项指标均未见显著升高（Ｐ＞０．０５）。提示：黄芩无致突变作用。 Explore the mutagenicity of Astragalus. Three doses (10 g/kg, 20 g/kg, 30 g/kg) of astragalus were used as the experimental group; the same volume of normal saline (NS) was used as the negative control group; 30 mg/kg of cyclophosphamide (CP) was used as the experimental group. ) As a positive control group. Micronucleus analysis was performed on the mother’s sternal bone marrow and fetal liver blood, and mouse blood lymphocytes were used for single cell gel electrophoresis (SCGE) test. Results Compared with the negative control group, there was no significant increase in various indicators of each dose of Astragalus membranaceus (P>0.05). Tip: Astragalus is not mutagenic.