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目的分析慢性乙型肝炎患者易患糖尿病的危险因素。方法选择49例肝炎合并2型糖尿病的患者及随机选取的51例普通慢性乙型肝炎患者作为对照,进行非条件逻辑逐步回归分析。结果经单因素非条件逻辑回归分析显示,年龄、糖尿病家族史、合并脂肪肝、病毒定量、AST ALT比值、γ-GT、白蛋白与球蛋白比值是慢性乙型肝炎合并糖尿病的危险因素.AST/ALT比值为保护因素。多因素非条件逻辑回归分析显示,年龄、合并脂肪肝、病毒定量和γ-GT为慢性乙型肝炎合并2型糖尿病的危险冈素。结论对慢性乙型肝炎患者,尤其是年龄较大者,应注意监测γ-GT、病毒定量,预防脂肪肝,以减少发生2型糖尿病的可能性。
Objective To analyze the risk factors of diabetes in chronic hepatitis B patients. Methods Forty-nine patients with hepatitis B and type 2 diabetes mellitus and 51 patients with chronic hepatitis B were randomly selected as the control, and stepwise logistic regression analysis was performed. Results By univariate non-conditional logistic regression analysis, age, family history of diabetes, combined fatty liver, viral quantitative, AST ALT ratio, γ-GT, albumin and globulin ratio were risk factors for chronic hepatitis B complicated with diabetes.AST / ALT ratio for the protection factor. Multivariate non-conditional logistic regression analysis showed that age, combined fatty liver, viral quantification and gamma-GT were risk factors for chronic hepatitis B complicated with type 2 diabetes. Conclusion For patients with chronic hepatitis B, especially those who are older, attention should be paid to the monitoring of γ-GT, quantification of the virus and prevention of fatty liver in order to reduce the possibility of type 2 diabetes.