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目的探讨重症支气管哮喘的病情评估和治疗。方法对我院2004年1月至2008年12月收治的47例重症支气管哮喘患者进行回顾性分析。结果病情完全缓解29例(61.7%),明显好转13例(27.7%)。死亡5例(10.6%),其中死于上消化道出血2例,呼吸衰竭2例,肾功能衰竭、肺部感染各1例。结论通过发病诱因、临床表现、血气分析等对病情进行评估,规范的激素治疗及扩张支气管药物的应用是治疗重症支气管哮喘成功的关键;必要时采用机械通气治疗可提高本病的抢救成功率。
Objective To evaluate the condition and treatment of severe bronchial asthma. Methods A retrospective analysis of 47 patients with severe bronchial asthma admitted to our hospital from January 2004 to December 2008 was performed. The results of complete remission in 29 cases (61.7%), significantly improved in 13 cases (27.7%). 5 cases died (10.6%), of which 2 died of upper gastrointestinal bleeding, 2 cases of respiratory failure, renal failure, 1 case of pulmonary infection. Conclusions The assessment of the condition by inducing the disease, clinical manifestations, blood gas analysis and so on, and the standard hormone therapy and the application of bronchial dilatation are the key to the successful treatment of severe bronchial asthma. If necessary, mechanical ventilation can improve the success rate of the rescue.