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本文报告了40名正常人、57例肾脏疾病、77例慢性肝病和31例结缔组织病患者的血清和尿β_2-M 测定结果(pharmacia β_2-M RIA Kit)。40名正常人平均年龄40岁,血清β_2-M均值1,487±372μg/L,尿β_2-M 为83±66μg/L,两者的正常上限分别为2,600μg/L 和280μg/L((?)+3SD)。各疾病组的血清β_2-M 水平(肾脏病还有尿β_2-M)均较正常对照组明显升高,且均与病情的严重程度或活动程度相平行。特别在累及免疫系统的疾病中,血清β_2-M 的动态监测有助于病情活动程度的判断,疗效估价和预后。
This article reports the results of serum and urinary β_2-M (pharmacia β_2-M RIA Kit) in 40 normal subjects, 57 patients with kidney disease, 77 patients with chronic liver disease and 31 patients with connective tissue disease. The average age of 40 normal people was 40 years old, the serum mean of β_2-M was 1,487 ± 372μg / L and the urine β_2-M was 83 ± 66μg / L, the upper limit of normal was 2,600μg / L and 280μg / L respectively + 3SD). Serum β_2-M levels (nephropathy and urine β_2-M) in all disease groups were significantly higher than those in the normal control group, and all were in parallel with the severity or degree of the disease. Especially in diseases involving the immune system, the dynamic monitoring of serum β_2-M contributes to the judgment of the degree of activity, evaluation of the curative effect and prognosis.