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采用全自动分析的方法,对40例原发性肝癌(PHC),219例其他疾病以及137例健康成人血清中α-L-岩藻糖苷酶(AFU)进行测定。正常人血清中酶活力呈正态分布,正常范围6.06±1.31U/L。PHC组较其他各组显著升高(l.70±9.45U/L,P<0.01).40例PHC患者AFU阳性率为72.5%,特异性为89.0%。AFU在AFP阴性的PHC患者中仍有76.9%阳性。
Automated analysis was used to determine the serum alpha-L-fucosidase (AFU) in 40 cases of primary liver cancer (PHC), 219 cases of other diseases, and 137 healthy adults. Normal human serum enzyme activity was normal distribution, the normal range of 6.06±1.31U/L. The PHC group was significantly higher than other groups (l.70±9.45 U/L, P<0.01). The AFU positive rate was 72.5% and the specificity was 89.0% in 40 patients with PHC. AFU is still 76.9% positive in AFP-negative PHC patients.