论文部分内容阅读
目的:观察中西医结合治疗急性化脓性扁桃体炎患者临床疗效观察及其安全性。方法:62例患者按照随机分组法分为观察组32例和对照组30例。观察组采用自拟中药汤剂联合阿莫西林克拉维酸钾治疗;对照组仅采用阿莫西林克拉维酸钾治疗。2组疗程均为5天。观察2组临床疗效,症状、体征消失时间,治疗前后体温变化和白细胞计数变化情况及治疗期间不良反应发生情况。结果:观察组疗程结束后总有效率93.75%高于对照组66.67%,差异有统计学意义(P<0.05);观察组咽部充血消退时间、退热时间、脓性分泌物消退时间短于对照组,差异均有统计学意义(P<0.05);2组治疗1天、治疗3天、治疗5天体温均较治疗前减少,差异均有统计学意义(P<0.05);观察组治疗3天、治疗5天后体温低于同期的对照组,差异均有统计学意义(P<0.05);2组白细胞计数治疗后均较治疗前减少,差异有统计学意义(P<0.05);观察组白细胞计数治疗后低于对照组,差异有统计学意义(P<0.05);治疗期间均未见明显不良反应发生。结论:中西医结合治疗急性化脓性扁桃体炎患者临床疗效良好,安全可靠,具有研究意义,值得临床运用。
Objective: To observe the clinical efficacy and safety of traditional Chinese and western medicine in the treatment of acute suppurative tonsillitis. Methods: Sixty-two patients were randomly divided into observation group (32 cases) and control group (30 cases). The observation group with self-made Chinese medicine decoction combined with amoxicillin and clavulanate potassium treatment; the control group only with amoxicillin and clavulanate potassium treatment. The two groups were treated for 5 days. The clinical curative effect, symptom, disappearance of signs and signs, changes of body temperature and leucocyte count before and after treatment and the occurrence of adverse reactions during the treatment were observed. Results: The total effective rate of observation group after treatment was 93.75% higher than 66.67% of control group, the difference was statistically significant (P <0.05); observation group throat congestion and remission time, antipyretic time, purulent secretions receded less than (P <0.05). In the two groups, the body temperature of one day, three days of treatment and five days of treatment decreased compared with that before treatment, the difference was statistically significant (P <0.05); the observation group (P <0.05). After 3 days of treatment, the body temperature was lower than that of the control group after 5 days of treatment (P <0.05). The white blood cell count of the two groups decreased after treatment compared with that before treatment, with significant difference (P <0.05) Group WBC count lower than the control group, the difference was statistically significant (P <0.05); no significant adverse reactions during the treatment. Conclusion: The combination of traditional Chinese and Western medicine in the treatment of acute suppurative tonsillitis patients with good clinical efficacy, safety and reliability, with research significance, is worth clinical application.