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目的了解徐州地区部分人群中庚型肝炎病毒(HGV)感染状况。方法以逆转录套式聚合酶链反应(RT-nestedPCR)对血清HGVRNA进行检测。结果HGVRNA阳性率在血液透析患者及丙型肝炎病人中分别为5.5%(11/31)、19.0%(19/100),显著高于自然人群1.3%(1/80)及职业献血员5.0%(2/40)。乙型肝炎及非甲-非戊型肝炎中HGVRNA阳性率分别为7.9%(5/63)和8.6%(3/35)。70.7%的HGVRNA阳性患者既往有输血(血制品)史。结论徐州地区人群中HGV感染较为广泛,其中血液透析患者和丙型肝炎病人中感染率较高。输血是徐州地区HGV感染传播的主要途径。
Objective To understand the prevalence of hepatitis G virus (HGV) in some population in Xuzhou area. Methods Serum HGV RNA was detected by reverse transcription-polymerase chain reaction (RT-nested PCR). Results The positive rate of HGVRNA in hemodialysis patients and hepatitis C patients was 5.5% (11/31) and 19.0% (19/100), respectively, which was significantly higher than that of natural population (1/80) And professional blood donors 5.0% (2/40). The positive rates of HGVRNA in hepatitis B and non-A-non-hepatitis E were 7.9% (5/63) and 8.6% (3/35) respectively. 70.7% of HGVRNA-positive patients had a history of transfusions (blood products). Conclusion The HGV infection in Xuzhou population is more extensive, among which hemodialysis patients and hepatitis C patients have a higher infection rate. Transfusion is the main route of HGV infection in Xuzhou.