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目的:探讨双环醇对抗痨药物造成的药物性肝损害的临床应用疗效。方法:选取我院2010年2月-2014年2月收治的80例抗痨药物性肝损害患者作为研究对象,随机分为观察组与对照组各40例,均给予常规药物治疗,观察组应用双环醇,对照组应用水飞蓟宾,对比两组患者临床治疗效果。结果:对比两组患者TBi L、ALT和AST恢复情况,其治疗总有效率无明显差异(p>0.05),无统计学意义。结论:抗痨药物性肝损害患者的预防过程中,应用双环醇的效果与水飞蓟宾基本相似,具有较好预防效果。
Objective: To investigate the clinical effect of bicyclol against drug-induced liver damage caused by 痨 drugs. Methods: Eighty patients with anti-TB drug-induced liver damage admitted from February 2010 to February 2014 in our hospital were selected and randomly divided into observation group and control group, 40 cases in each group were given conventional drug treatment and observation group Bicyclol, control group, silybin, compared the clinical efficacy of two groups of patients. Results: There was no significant difference in the total effective rate (p> 0.05) between the two groups in the recovery of TBiL, ALT and AST. There was no statistical significance. Conclusion: The anti-tuberculosis drugs in patients with liver damage prevention process, the application of bicyclol and silibinin similar effect with good preventive effect.