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In recent years,intravascular ultrasound(IVUS) follow-up is always used in the evaluation of the development of atherosclerosis,and it can also be used as the endpoint of drug therapy in clinical observation.Since 1994,the first statin lipid-lowering 4S experiment results was reported,the following statin for lipid-lowering tests represented by REVERSAL PROVE-IT,TNT,IDEAL,ASTEROID and JUPITER strongly confirmed that further reduce the efficacy of low-density lipoprotein cholesterol(LDL-C)(to enhance the lipid-lowering treatment) access to increase effect of the cardiovascular protection and also reverse the plaques’ progress.But scholars’ opinions on the merits and demerits of enhance statin cholesterol-lowering therapy has been in debate.We review the recent work on statins and reversal of arterial plaques for a number of clinical studies.
In recent years, intravascular ultrasound (IVUS) follow-up is always used in the evaluation of the development of atherosclerosis, and it can also be used as the endpoint of drug therapy in clinical observation. Since 1994, the first statin lipid-lowering 4S experiment results was reported, the following statin for lipid-lowering tests represented by REVERSAL PROVE-IT, TNT, IDEAL, ASTEROID and JUPITER strongly confirmed that further reduce the efficacy of low-density lipoprotein cholesterol (LDL-C) (to enhance the lipid progress consult on the cardiovascular protection and also reverse the plaques ’progress.But scholars’ opinions on the merits and demerits of enhancing statin cholesterol-lowering therapy has been in debate.We review the recent work on statins and reversal of arterial plaques for a number of clinical studies.