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目的:调查分析门诊处方中不合理应用抗菌药物的情况。方法:随机抽取2007年门诊处方324 583张,对处方的临床诊断和抗菌药物使用,包括用法、用量、配伍及联合用药等情况进行分类统计和分析。结果:抽检处方中,使用抗菌药物的处方有133 728张,占处方总数41.2%;联合用药占抗菌药物处方的35.58%,其中以二联应用比例最大;抗菌药物不合理应用处方63 815张,占抗菌药物处方47.72%。主要表现为对药物及病原菌了解不足,抗菌药物应用指征太松,以过度应用为主要倾向。结论:门诊抗菌药物存在不合理使用现象,应进一步加强临床用药督导。
Objective: To investigate and analyze the unreasonable use of antibacterials in outpatient prescriptions. Methods: A total of 324 583 outpatient prescriptions were randomly selected in 2007 to classify and analyze the prescriptions for clinical diagnosis and antimicrobial use, including usage, dosage, compatibility and combination. Results: Among the sampling prescriptions, there were 133 728 prescriptions for antibiotics, accounting for 41.2% of the total number of prescriptions; 35.58% of the prescriptions for antimicrobial drugs were used in combination with the largest proportion in two groups; 63 815 prescriptions of antibiotics were unreasonably used, Antibiotics accounted for 47.72% of prescriptions. Mainly manifested as inadequate understanding of drugs and pathogens, antimicrobial indications for use too loose, the over-application as the main tendencies. Conclusion: There is an irrational use of outpatient antibacterial drugs, and clinical drug supervision should be further strengthened.