随着硅油在眼科手术中的应用 ,硅油填充术后的角膜病变已日渐受到重视。主要表现为角膜内皮失代偿和角膜带状变性。角膜病变的发生与多次手术和术后硅油进入前房与角膜内皮接触有较大关系。本文就硅油引发的角膜病变的发生率、影响因素、病理改变、临床表现、发生机制、预防措施及治疗手段作一综述 With the application of silicone oil in ophthalmic surgery, corneal disease after silicone oil filling has been paid more and more attention. The main manifestations of corneal endothelial decompensation and corneal degeneration. Occurrence of corneal disease with multiple surgeries and postoperative silicone oil into the anterior chamber and corneal endothelial contact have a greater relationship. In this paper, the incidence of silicone-induced corneal lesions, influencing factors, pathological changes, clinical manifestations, mechanism of occurrence, preventive measures and treatment methods are reviewed