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目的:进一步证实人乳头瘤病毒(HPV)与膀胱癌的相关性。方法:采用高敏感聚合酶链反应(PCR)技术检测42例膀胱癌组织标本,并用20例前列腺增生症患者之正常膀胱组织标本作对照。结果:膀胱癌HPV感染率为52.4%,正常膀胱组织标本HPV感染率为10.0%,其中1例阳性者1年后发生膀胱癌。结论:HPV感染与膀胱癌有一定的相关性,并在膀胱癌的发生中起着相关作用。
Objective: To further confirm the correlation between human papillomavirus (HPV) and bladder cancer. Methods: Twenty-four cases of bladder cancer were examined by high sensitive polymerase chain reaction (PCR) technique. The normal bladder tissues of 20 patients with benign prostatic hyperplasia were used as controls. Results: The infection rate of HPV in bladder cancer was 52.4%. The HPV infection rate in normal bladder tissue was 10.0%. One of them had bladder cancer one year later. Conclusion: HPV infection has some correlation with bladder cancer, and plays a related role in the occurrence of bladder cancer.