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目的:验证注射用头孢他啶与硫酸镁注射液的配伍变化情况,对有关论著中提及此两药配伍变化的矛盾性结论进行分析。方法:在10,25℃以及35℃条件下,模拟临床用药,于不同的时间观察不同质量浓度两药配伍后的外观变化。结果:两药采用9.0mg/mL氯化钠注射液稀释配伍后,在不同温度、不同浓度的配伍液中其外观均未发生结晶、沉淀、气泡等变化。结论:两药稀释配伍后未发生外观变化。
OBJECTIVE: To verify the compatibility between ceftazidime injection and magnesium sulfate injection and to analyze the contradictory conclusions concerning the compatibility of the two drugs in the related articles. Methods: The clinical medication was simulated at 10, 25 and 35 ℃, and the appearance changes of the two drugs with different mass concentration were observed at different times. Results: After the two drugs were diluted and mixed with 9.0mg / mL sodium chloride injection, no change in appearance, precipitation, bubbles and the like were observed in different temperature and different concentration of compatibility liquid. Conclusion: There is no appearance change after the two drugs are diluted and matched.