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目的 探讨腹腔镜与开放式十二指肠穿孔修补术治疗十二指肠溃疡合并穿孔患者的临床疗效.方法 选取 70例十二指肠溃疡合并穿孔的患者,将其采用随机数字表法分为两组,每组35例.研究组患者行腹腔镜十二指肠穿孔修补术,对照组行开放式十二指肠穿孔修补术,比较两组患者临床指标及并发症情况.结果 两组患者均顺利实施手术并康复出院,对照组患者住院费用和手术时程上明显低于研究组;而研究组患者在住院时间、排气时间、术中出血量、术后并发症、术后镇痛药物使用率指标均明显低于对照组,差异均有统计学意义(均P<0.05).结论 腹腔镜十二指肠穿孔修补术治疗十二指肠溃疡并穿孔,对患者的创伤小,恢复快,并发症少,安全性高,疗效确切.“,”Objective To investigate the laparoscopic and open gastroduodenal perforation repair in the treatment of duodenal ulcer and perforation in patients with clinical efficacy.Methods A total of 70 patients with duodenal ulcer perforation in our hospital and patients,which were randomly divided into two groups,35 patients in each group.The study group were treated with laparoscopic gastroduodenal perforation repair,the control group open gastroduodenal perforation repair surgery,compared two groups of patients with clinical indicators and complications.Results Two groups of patients were operated successfuly and were discharged from the hospital,hospitalization expenses and the control group was significantly lower than that of group process;while the study group in hospitalization time, exhaust time,intraoperative bleeding volume,postoperative complications,postoperative analgesia drug use rate were significantly lower than the control group,the differences were statisticaly significant(P<0.05).Conclusion Laparos- copic gastroduodenal perforation repair in the treatment of peptic ulcer perforation patients,for patients with minor trauma,quick recovery,less complication,high safety,curative effect.