子前期孕妇血清及胎盘中IL-6和IL-17的表达及意义

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目的通过观测子前期孕妇血清和胎盘中IL-6和IL-17水平的变化,探讨这两种细胞炎性因子与子前期发病的关系。方法采用酶联免疫吸附法(ELISA)分别测定30例子前期孕妇(子前期组)和30例正常晚期妊娠孕妇(对照组)血清中IL-6和IL-17的浓度。采用免疫组织化学法测定子前期组和对照组胎盘组织中IL-6和IL-17的表达水平。结果子前期组血清中IL-6和IL-17浓度均高于对照组,差异均有统计学意义(P〈0.01)。IL-6在子前期组胎盘中的表达明显低于对照组,差异有统计学意义(P〈0.05
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