手足口病在国外早有报告流行,但在国内确定有本病是1983年由天津市卫生防疫站最先证实的,是一种以疱疹伴发热,在儿童中好发的疾病。病原学:自病儿的疱疹液标本中分离出稳定病毒株“津防H—837”,病儿恢复期血清中该病毒抗体上升。经鉴定“津防H—837”为柯萨奇A16型肠道病毒。 Hand, foot and mouth disease has long been reported in foreign countries, but it is confirmed in the country that the disease was first confirmed by the Tianjin Municipal Health and Anti-Epidemic Station in 1983, and is a disease that occurs in children with herpes fever. Etiology: From herpes herpes fluid samples isolated stable virus strain “Tianjin anti-H-837”, convalescent sick child serum antibody increased. It was identified as “Tianjin anti-H-837” Coxsackie A16 enterovirus.