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1例55岁女性患者因肝癌、肝硬化静脉滴注苦参碱葡萄糖注射液250 ml,1次/d。次日出现水样腹泻,立即停药。第3天腹泻消失。间隔2 d后,患者再次静脉滴注苦参碱葡萄糖注射液250 ml,1次/d。第3天发生严重无痛性水样腹泻。给予大蒜素、诺氟沙星、复方地芬诺酯、头孢西丁,但腹泻无缓解。第4天停用苦参碱葡萄糖注射液。次日,腹泻停止。
A 55-year-old woman received intravenous infusion of 250 mg matrine and glucose once a day for liver cancer and cirrhosis. The next day there was watery diarrhea and immediate withdrawal. Diarrhea disappeared on the third day. After an interval of 2 days, the patient again intravenously injected 250 ml of matrine and glucose injection once a day. Severe and painless watery diarrhea occurred on the third day. Give allicin, norfloxacin, diphenoxylate compound, cefoxitin, but no diarrhea relief. Day 4 Disable matrine and glucose injection. The next day, diarrhea stopped.