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目的总结儿童川崎病的特点,提高对本病的认识,以期发现对早期诊断有重要价值的临床特征及恰当的治疗方法。方法对56例川崎病患儿的临床表现、辅助检查及治疗情况进行回顾性分析。结果指(趾)端肿胀脱皮,口腔黏膜潮红、皲裂,眼结膜充血,肛周红,卡瘢红等在本病比较有诊断价值;而后4项具有早期诊断意义。静脉用丙种球蛋白(IVIG)早起应用(<10d)可预防冠状动脉损害的发生;2.0g/kg.d单日1次的用药方法能更快减轻症状,控制发热。结论早期大剂量应用静脉丙种球蛋白及口服阿司匹林可迅速有效缓解症状,减少冠状动脉病变的发生率。
Objective To summarize the characteristics of children with Kawasaki disease and to raise awareness of the disease so as to find out the clinical features and appropriate treatment methods that have important value in early diagnosis. Methods Retrospective analysis of 56 cases of Kawasaki disease in children with clinical manifestations, laboratory examinations and treatment. Results Finger swelling and peeling, oral mucosa flushing, chapped, conjunctival hyperemia, perianal red, card scarred more in the diagnosis of the disease more; and then 4 with early diagnosis. Intravenous administration of gammaglobulin (IVIG) early (<10d) prevented the development of coronary artery lesions; and administration of 2.0g / kg.d, once daily, reduced symptoms more rapidly and controlled fever. Conclusion Early high-dose intravenous gamma globulin and oral aspirin can quickly and effectively relieve symptoms and reduce the incidence of coronary lesions.