论文部分内容阅读
目的:观察七氟烷复合盐酸吗啡在小儿保留自主呼吸全身麻醉中对小儿患者血流动力学波动、术中呼吸抑制、术后苏醒时间以及苏醒期躁动情况的影响。方法:选择年龄在2~6岁、ASAⅠ-Ⅱ的小儿手术病例64例。随机分为观察组32例:七氟烷复合小剂量盐酸吗啡(诱导剂量0.1 mg·kg~(-1),间断剂量0.03 mg·kg~(-1)静脉注射)麻醉;对照组32例:氯胺酮复合咪达唑仑麻醉;监测血流动力学、呼吸抑制评分、躁动评分、平均PACU监护时间等。结果:64例患儿中,麻醉时间30~145 min,麻醉、手术均顺利完成,无严重麻醉并发症发生;观察组(32例)与对照组(32例)各时间段的收缩压(mmHg)、心率(bpm)、平均麻醉诱导时间,平均呼吸抑制评分,进入辅助呼吸组例数,平均麻醉苏醒时间,苏醒期躁动平均评分,苏醒期平均镇静评分,PACU恶心、呕吐病例发生率,平均PACU监护时间,麻醉后72 h随访阳性率数据结果差异有统计学意义(P<0.05)。结论:七氟烷复合盐酸吗啡用于小儿保留自主呼吸的全身麻醉具有诱导、苏醒快,且过程平顺,对循环呼吸的影响小,并发症少,苏醒期躁动少,麻醉后护理方便,加快患儿康复,易于被患儿和患儿家属接受的优点。
Objective: To observe the effects of sevoflurane combined with morphine hydrochloride on hemodynamic fluctuation, intraoperative respiratory depression, postoperative recovery time and wakefulness in children undergoing spontaneous breathing in general anesthesia. Methods: A total of 64 pediatric cases with ASAⅠ-Ⅱ were selected from 2 to 6 years old. Thirty rabbits were randomly divided into observation group (n = 32): sevoflurane combined with small dose of morphine hydrochloride (inducing dose of 0.1 mg · kg -1, intermittent dose of 0.03 mg · kg -1) intravenously; control group of 32 patients: Ketamine combined with midazolam anesthesia; monitor hemodynamics, respiratory depression score, restlessness score, average PACU monitoring time and so on. Results: In 64 cases, the anesthesia time was 30 ~ 145 min, anesthesia and operation were completed successfully, and no severe anesthesia complications occurred. The systolic blood pressure (mmHg) in observation group (32 cases) and control group (32 cases) ), Heart rate (bpm), average time to induction of anesthesia, mean respiratory depression score, number of patients who entered the assisted breathing group, mean time to anesthesia recovery, average rest period agitation, mean sedation recovery period, incidence of PACU nausea and vomiting, PACU monitoring time, 72 h after anesthesia follow-up positive rate data were statistically significant differences (P <0.05). CONCLUSIONS: Sevoflurane combined with morphine hydrochloride is used to induce general anesthesia in children with spontaneous respiration. It regains fast recovery and has a smooth process with little effect on circulatory respiration, less complications, less agitation during anesthesia, convenient nursing after anesthesia, Children rehabilitation, easy to accept the advantages of children and their families.