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使用中药丸剂治疗疾患,在我国已有悠久的历史。目前中药丸剂根据所用赋型剂的不同,可分为水丸、蜜丸、糊丸、蜡丸等四种。丸剂的应用,取其在体内缓慢崩解,逐渐释放药物。为了探讨丸剂释放药效的规律,作了一些丸剂的崩解度实验,为制定中药丸剂标准规格打下基础。现将实验方法及测定结果报导如下。实验方法及结果中药丸剂崩解时限的测定,目前尚无成熟方法可循,现采用中国药典(1963年版)二部附录2页,测定片剂崩解时限的方法进行测定丸剂,即取丸剂置中国药典(1963年
The use of traditional Chinese medicine pills to treat diseases has a long history in China. At present, traditional Chinese medicine pills can be divided into water pills, honey pills, paste pills, and wax pills according to the different excipients used. The application of pills, taking it slowly disintegrate in the body, gradually releases the drug. In order to discuss the law of the release of boluses, some experiments on the disintegration of boluses were made to lay the foundation for the formulation of standard granules for traditional Chinese medicine pills. The experimental methods and measurement results are reported below. Experimental methods and results Determination of the disintegration time limit of traditional Chinese medicine pills There are no mature methods available at present. Now we use the Chinese Pharmacopoeia (1963 edition), Appendix 2, page 2 to determine the disintegration time limit of tablets to determine the pills. Chinese Pharmacopoeia (1963