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目的:探讨和分析奥曲肽用于治疗急性重症胰腺炎的临床疗效。方法:选择2009年7月至2012年7月就诊于我院的60例急性重症胰腺炎患者,随机分为对照组和观察组,对照组给予禁食、胃肠减压、营养支持等常规治疗;观察组在对照组常规治疗的基础上给予持续静滴奥曲肽,观察两组腹痛、腹胀缓解时间等临床表现和住院天数的差别以及两组的显效情况,对比临床效果。结果:奥曲肽治疗重症急性胰腺炎可缩短腹痛、腹胀等症状的缓解时间及住院天数,观察组治疗的总有效率明显高于对照组,经统计学分析具有显著性差异(P<0.05)。结论:奥曲肽是治疗急性重症胰腺炎的一种有效药物,值得临床推广使用。
Objective: To investigate and analyze the clinical efficacy of octreotide in the treatment of acute severe pancreatitis. Methods: Sixty patients with severe acute pancreatitis treated in our hospital from July 2009 to July 2012 were randomly divided into control group and observation group. The control group was given conventional therapy such as fasting, gastrointestinal decompression and nutrition support . The observation group was given continuous intravenous infusion of octreotide on the basis of routine treatment in the control group. The difference between the clinical manifestations and hospitalization days in the two groups was observed, as well as the effective conditions of the two groups. The clinical effects were compared. Results: Octreotide treatment of severe acute pancreatitis can reduce the time of abdominal pain and abdominal distension symptoms and hospital stay, the total effective rate of observation group was significantly higher than the control group, statistically significant difference (P <0.05). Conclusion: Octreotide is an effective drug for the treatment of acute severe pancreatitis and is worthy of clinical promotion.