据《柳叶刀》杂志报道,两项不相关的研究表明,用于治疗轻度抑郁的常用药圣约翰草对分别用于HIV感染和心脏移植的两种药的效果有影响。尽管两项研究均为小样本研究,但在治疗HIV感染和心脏移植患者时应对上述结果予以注意。 美国国立卫生研究院(NIH)的研究人员就圣约翰草对用于HIV感染的蛋白酶抑制剂indinavir作用的影响进行了评价。 According to The Lancet, two unrelated studies have shown that St. John’s wort, a commonly-used drug used to treat mild depression, has an effect on the efficacy of the two drugs used for HIV infection and heart transplantation respectively. Although both studies are small sample studies, attention should be paid to these results in the treatment of HIV infection and heart transplant patients. Researchers from the National Institutes of Health (NIH) evaluated the effect of St. John’s wort on the indinavir effect of the protease inhibitor used in HIV infection.