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以RT PCR法分析脂肪细胞载脂蛋白E(apoE)基因的表达,发现肥胖儿童脂肪细胞apoE基因表达水平显著下调,重度及中心性肥胖尤甚,提示apoE基因可能与肥胖密切相关。
The expression of apolipoprotein E (apoE) gene in adipocytes was analyzed by RT-PCR. The apoE gene expression was significantly down-regulated in obese children, especially in severe and central obesity, suggesting that apoE gene may be closely related to obesity.