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目的:探讨连续性血液净化(CBP)治疗重症急性胰腺炎(SAP)合并MODS的疗效。方法:选取我院2009年1月~2013年5月收治的30例重症急性胰腺炎(SAP)合并MODS的患者,在综合治疗的基础上,进行连续性血液净化(CBP)治疗3~7天,观察治疗前后患者的症状改善及各项生化指标情况。结果:通过CBP治疗,患者的心动过速、呼吸窘迫、腹痛、腹胀等症状得到有效的缓解,血清总胆红素、丙氨酸氨基转移酶、血清淀粉酶、尿素氮、肌酐、C-反应蛋白较治疗前显著降低(P<0.05),患者酸中毒及低氧血症得到有效纠正,30例患者,26例治愈或好转,4例死亡。结论:针对重症急性胰腺炎(SAP)合并MODS的患者,通过连续性血液净化进行治疗,可改善患者的临床症状,降低死亡率,保证患者的生命健康。
Objective: To investigate the curative effect of continuous blood purification (CBP) on severe acute pancreatitis (SAP) combined with MODS. Methods: Thirty patients with severe acute pancreatitis (SAP) and MODS admitted to our hospital from January 2009 to May 2013 were enrolled in this study. Patients were treated with continuous blood purification (CBP) for 3 to 7 days on the basis of comprehensive treatment , Observe the patients before and after treatment to improve the symptoms and the biochemical indicators. Results: CBP treatment effectively alleviated the symptoms of tachycardia, respiratory distress, abdominal pain and abdominal distension. Serum total bilirubin, alanine aminotransferase, serum amylase, urea nitrogen, creatinine, C-reaction The protein was significantly lower than before treatment (P <0.05), acidosis and hypoxemia were effectively corrected in 30 patients, 26 patients were cured or improved, and 4 patients died. Conclusion: Patients with severe acute pancreatitis (SAP) combined with MODS can be treated with continuous blood purification to improve the clinical symptoms, reduce mortality and ensure the patient’s life health.