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目的研究补肾健脾法治疗不明原因复发性流产的临床疗效,为临床治疗提供参考依据。方法抽取2010年1月-2014年3月兰州市第二人民医院妇产科收治的不明原因复发性流产患者56例为研究对象,按患者自愿原则分为研究组和对照组,每组各28例。对照组进行黄体酮肌内注射保胎治疗,研究组在对照组治疗基础上应用补肾健脾法综合治疗。统计两组患者临床疗效和实验室相关检查结果。结果研究组总有效率为96.43%,显著高于对照组的78.57%(χ2=3.89,P<0.05)。治疗后,研究组Th1/Th2比值为(0.36±0.41),显著低于对照组的(1.09±0.51)(t=3.73,P<0.05)。结论补肾健脾法联合黄体酮注射可有效提高不明原因复发性流产患者的临床治疗效果,延长妊娠时间,显著降低体内Th1/Th2比值,可在临床治疗中推广应用。
Objective To study the clinical efficacy of Bushen Jianpi method in the treatment of unexplained recurrent spontaneous abortion and provide a reference for clinical treatment. Methods Fifty-six patients with unexplained recurrent spontaneous abortion admitted to Department of Obstetrics and Gynecology, Second People’s Hospital of Lanzhou from January 2010 to March 2014 were selected as study subjects and divided into study group and control group according to their voluntary principle example. Control group intraperitoneal injection of progesterone miscarriage treatment, the study group in the control group based on the application of kidney and spleen method of comprehensive treatment. Statistics of two groups of patients with clinical efficacy and laboratory-related test results. Results The total effective rate was 96.43% in the study group, which was significantly higher than 78.57% in the control group (χ2 = 3.89, P <0.05). After treatment, the Th1 / Th2 ratio in the study group was (0.36 ± 0.41), significantly lower than that in the control group (1.09 ± 0.51) (t = 3.73, P <0.05). Conclusion Bushenjianpi combined with progesterone injection can effectively improve the clinical treatment effect of patients with unexplained recurrent spontaneous abortion, prolong the pregnancy time and significantly reduce the Th1 / Th2 ratio in vivo, which can be widely used in clinical treatment.