目的探讨单纯对症支持疗法治疗和此治疗加思密达结合叶酸、复合维生素B及维生素K3治疗婴幼儿腹泻的临床疗效。方法将腹泻患儿120例按简单随机抽样法分为:观察组53例,对照组67例。对照组采用常规西医对症治疗,包括调整饮食结构、纠正脱水及电解质紊乱等对症支持疗法。观察组在常规对症支持疗法基础上加服思密达结合叶酸、复合维生素B及维生素K3,疗程5~7 d。结果观察组总有效率为92.4%;对照组总有效率为76.2%。两组有效率差异有统计学意义(P均<0.01)。结论常规对症支持疗法加服思密达结合叶酸、复合维生素B及维生素K3治疗婴幼儿腹泻疗效确切,效果满意,且患儿无痛苦,安全性高,值得推广应用。 Objective To investigate the clinical efficacy of simple symptomatic and supportive therapy and this treatment combined with gastacide combined with folic acid, vitamin B and vitamin K3 in the treatment of infantile diarrhea. Methods 120 cases of children with diarrhea were divided into simple random sampling method: observation group 53 cases, control group 67 cases. The control group used conventional Western medicine symptomatic treatment, including adjusting diet structure, correcting symptomatic supportive therapy such as dehydration and electrolyte imbalance. The observation group received Smectite combined with folic acid, vitamin B complex and vitamin K3 on the basis of routine symptomatic supportive therapy for 5 to 7 days. Results The total effective rate was 92.4% in observation group and 76.2% in control group. The difference between the two groups was statistically significant (P all <0.01). Conclusion Conventional symptomatic supportive therapy combined with smecta combined with folic acid, vitamin B and vitamin K3 in the treatment of infantile diarrhea has definite curative effect and satisfactory results. Children with painlessness and high safety are worth popularizing and applying.