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目的对15例阴囊Paget病的临床表现,治疗方法及其预后进行分析。方法14例行病灶广泛切除,7例证实有腹股沟淋巴结转移的患者中5例行淋巴结清除术。4例患者由于创面缺损较大而行植皮,筋膜皮瓣及带血管蒂的腹直肌岛状肌皮瓣修复。结果7例有腹股沟淋巴结转移的患者中6例死亡,其中5例在5年内死亡。1例失访。无腹股沟淋巴结转移者均存活。结论阴囊Paget病的治疗首选手术切除。一旦有淋巴结转移,其5年生存率较低。
Objective To analyze the clinical manifestations, treatment and prognosis of Paget’s disease in 15 cases of scrotum. Methods A total of 14 routine lesions were extensively resected. Lymphadenectomy was performed in 5 of 7 patients with confirmed inguinal lymph node metastases. In 4 patients, skin grafts, fascia flaps, and pedicled myocutaneous island myocutaneous flaps were repaired due to the large defect of the wound. Results Six of the seven patients with inguinal lymph node metastases died, and five of them died within five years. 1 patient lost. No inguinal lymph node metastasis were survival. Conclusion The treatment of scrotal Paget’s disease is the first choice of surgical resection. Once there is lymph node metastasis, its 5-year survival rate is lower.