此病多为单发,常见于面部和手背等部位。以往均以手术治疗,放疗尚无报导。本例经用放疗治愈,特报告如下: 患者刘××,女,50岁,1986年2月起病,右上唇皮肤生小米粒大小硬结,四个月后长至小指头大小。表面皮色正常,微有痒感,中心开始角化。1986年6月在哈医大二院经病理检查为角化性棘皮瘤,预给手术切除并植皮治疗,将损伤面容,患者拒绝手术。于86年7月来我院就诊,右上唇肿物,坚硬如石,边界清楚,肿物为2.5×3.5厘米,高出 The disease is mostly single, common in the face and back of the hand and other parts. Surgical treatment has been used in the past and radiotherapy has not been reported. This case was cured by radiotherapy. The special report was as follows: The patient Liu X, female, 50 years old, became ill in February 1986. The upper right lip skin had a small grain size induration and grew to a small finger size four months later. The skin color is normal, slightly itching, and the center begins to keratinize. In June 1986, he was diagnosed as a keratoacanthoma by histopathological examination in the Second Affiliated Hospital of Harbin Medical University. He was given surgical resection and skin grafting to treat his face. He came to our hospital in July, 86, with a right upper lip mass, hard as a stone, clear boundary and a mass of 2.5 x 3.5 cm.