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以往认为红细胞只参与呼吸功能,没有免疫功能。事实上红细胞有许多与免疫有关的物质(如CR1、CR3、CD58、CD59、IL-8受体、DAF、SOD酶等),数目众多、自成系统。红细胞有识别、粘附、浓缩抗原加速清除CIC的能力,参与机体免疫调控,并有完整的自我调控系统。许多疾病(如SLE)免疫发病机理中,红细胞免疫缺陷占有很重要的地位。研究有关红细胞免疫对全面认识机体免疫系统和免疫网络具有一定的意义。 1981年美国学者Siegel在前人研究的基础上发现红细胞有多种免疫功能,红细胞可粘附胸腺细胞,并发现血清中存在红细胞免疫粘附抑制因子,是一种不耐热的大分子糖蛋白。在SLE患者中
In the past that red blood cells only participate in respiratory function, there is no immune function. In fact, many of the red blood cells and immune-related substances (such as CR1, CR3, CD58, CD59, IL-8 receptors, DAF, SOD enzymes, etc.), a large number of self-formed system. Erythrocytes have the ability to identify, adhere, and concentrate antigens to speed up the removal of CIC, participate in the immune regulation of the body, and have a complete self-regulation system. Many diseases (such as SLE) immune pathogenesis, red blood cell immune defects play a very important position. Research on erythrocyte immunity is of certain significance for comprehensive understanding of the immune system and immune network in the body. In 1981, American scholar Siegel found on the basis of previous studies that erythrocytes have a variety of immune functions, erythrocytes can adhere to thymocytes and found that erythrocyte immune adhesion inhibitor exists in serum, which is a thermolabile macromolecular glycoprotein . In SLE patients