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情绪在日常生活中对人的影响巨大,而情绪反应引发疾病并影响其发展的机制尚未清晰。为追本求源,情绪反应动物模型的建立显得尤为重要。但是从情绪模型诞生起,就存在造模方法的缺陷,如存在躯体的应激。同时,模型的评价也不尽客观。而寻找其解决方法对于完善模型和扩大模型的应用极为重要。现对常见的情绪反应动物模型的造模方法和评价方法进行综述,以期为情绪反应动物模型的研制提供可资借鉴的思路与方法学参考。
Emotions have a huge impact on people in their daily lives, and the mechanism by which emotional reactions cause illness and affect its development is not yet clear. In order to pursue this source, the establishment of animal model of emotional response is particularly important. However, from the birth of the emotional model, there are defects in modeling methods, such as the existence of physical stress. At the same time, the evaluation of the model is not objective. Finding the solution to this problem is extremely important for improving the model and for expanding the application of the model. Now we reviewed the methods and evaluation methods of the common animal model of emotional response, with a view to providing ideas and methodological references for the development of animal models of emotional response.