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目的比较阿奇霉素与红霉素治疗细菌性呼吸道感染的临床疗效。方法选取2011年10月—2013年7月我院收治的细菌性呼吸道患者62例,将其按照随机数字表法分为阿奇霉素组和红霉素组,各31例。阿奇霉素组给予阿奇霉素治疗,红霉素组给予红霉素治疗。比较两组患者疗效,并进行安全性评价。结果阿奇霉素组总有效率为96.8%(30/31),高于红霉素组的77.4%(24/31)(P<0.05)。阿奇霉素组不良反应发生率为6.5%(2/31),低于红霉素组的25.8%(8/31)(P<0.05)。结论阿奇霉素治疗细菌性呼吸道感染较红霉素疗效显著,且安全性高,值得在临床中推广应用。
Objective To compare the clinical efficacy of azithromycin and erythromycin in the treatment of bacterial respiratory infection. Methods Sixty-two patients with bacterial respiratory tract admitted to our hospital from October 2011 to July 2013 were divided into azithromycin group and erythromycin group according to the random number table method, and each group had 31 cases. Azithromycin for azithromycin treatment group, erythromycin group for erythromycin treatment. The curative effect of two groups was compared and the safety evaluation was carried out. Results The total effective rate of azithromycin group was 96.8% (30/31), which was higher than that of erythromycin group (77.4%, 24/31) (P <0.05). The rate of adverse reactions in azithromycin group was 6.5% (2/31), which was lower than 25.8% (8/31) in erythromycin group (P <0.05). Conclusion Azithromycin treatment of bacterial respiratory tract infection than erythromycin significant effect, and high safety, it is worth in the clinical application.