注射用甲泼尼龙琥珀酸钠致严重过敏反应1例

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甲泼尼龙琥珀酸钠(methylprednisolone sodium succinate)为甲泼尼龙的前体化合物,极易溶于水,克服了甲泼尼龙极难溶于水的缺点~[1],适用于需要快速达到较高血药浓度的静脉给药~[2]。甲泼尼龙琥珀酸钠为中效糖皮质激素,在体内迅速水解后发挥作用,临床上用于抗炎、免疫抑制、休克和内分泌失调等的治疗~[3,4]。甲泼尼龙琥珀酸钠说 Methylprednisolone sodium succinate, a precursor compound of methylprednisolone, is highly soluble in water and overcomes the disadvantage that methylprednisolone is extremely poorly soluble in water [1] and is suitable for applications where rapid uptake is required Intravenous drug concentration ~ [2]. Methylprednisolone sodium succinate is a mid-acting glucocorticoid that acts rapidly after in vivo hydrolysis and is clinically used in the treatment of anti-inflammatory, immunosuppressive, shock and endocrine disorders [3,4]. Methylprednisolone sodium succinate said
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