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目的:从影像学上严格评价现有的相关文献，比较正畸治疗后根管治疗牙和活髓牙牙根吸收程度是否存在差异。方法:检索从影像学上比较正畸后根管治疗牙和活髓牙牙根吸收的文献，按照纳入标准筛选文献，分析纳入研究的特征，评价研究的质量，定量分析和比较正畸后根管治疗牙和活髓牙牙根吸收程度。结果:6篇研究被纳入，研究间存在比较明显的异质性(n P＝0.1，n I2＝46%)，按照正畸前的牙根状况作亚组分析，发现正畸前的牙根异常是明显的异质性因素，排除1篇低质量且有明显异质性的研究，其余5篇被纳入最终的Meta分析，结果显示正畸后的牙根吸收量在根管治疗牙和活髓牙之间无显著差别[MD＝0.04(-0.06，0.13)，n Z＝0.80，n P＝0.42]。按照牙齿类型和测量方法的亚组分析显示各亚组间都无显著差异(分别为n P＝0.63和n P＝0.62)。n 结论:当评价和比较正畸治疗后根管治疗牙和活髓牙牙根吸收程度时，要考虑正畸前的牙根状况。正畸前的牙根异常，如牙创伤史和牙根吸收史，是影响评价正畸后牙根吸收程度的明显干扰因素。对现有研究的分析显示，在正畸治疗前牙根正常的前提下，正畸后根管治疗牙和活髓牙的牙根吸收程度无明显差别。在临床上根尖片和CBCT都适用于评价牙根外部根尖吸收。由于纳入的研究数量有限，并且仍存在方法学差异，因此需要更多高质量研究来提供更可靠的证据。“,”Objective:To critically assess the available literature and radiographically investigate the difference of the extent of orthodontically induced root resorption between root-filled and vital pulp teeth.Methods:Literaturewhich radiographically compared the extent of orthodontically induced root resorption in root-filled and vital pulp teeth werecollected according to inclusion criteria. Characteristics and quality of the selected literature were assessed. Comparison of the amount of orthodontically induced root resorption in root-filled and vital pulp teeth was conducted quantitatively.Results:Significant heterogeneity existed among the initially included six studies (n P=0.1, n I2=46%). Subgroup analysis according to differentpretreatment state of root tissue showed abnormal root prior to orthodontic treatment was the major confounding factor.Therefore, one articlewith lowquality was eliminated, leaving five articles included in the final meta-analysis. The extent of orthodontically induced root resorption in root-filled teeth was no less than vital pulp teeth [MD=0.04(-0.06, 0.13), n Z=0.80, n P=0.42]. There was no statistical difference between subgroups according todifferenttooth formsand measure methods (n P=0.63 and n P=0.62, respectively).n Conclusions:To investigate the difference of the extent of orthodontically induced root resorption between root-filled and vital pulp teeth, it is necessary to consider the status of the pretreatment roots, such as dental injury and root resorption history.According to the available evidence, withnormal roots at the beginningof orthodontic treatment, there is no statistical difference in the extent of orthodontically induced root resorption between root-filled and vital pulp teeth. Both periapical and CBCT can be clinically used for root resorption evaluation.Because of the small number of available articles with different methodology, more articles with high quality are needed to provide reliable evidence.