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脱氧镰刀雪腐烯醇(Deoxynivalenol,DIN)是单端孢霉烯族毒素之一,在自然界中广泛存在。目前被认为是存在于赤霉病小麦中的主要天然毒素之一。它可引起人畜中毒。虽然它的毒性较同族其它真菌毒素小,但由于它广泛存在并大量污染粮食,对人畜构成很大危害。联合国粮农组织和世界卫生组织1973年联合召开的第三次食品添加剂和污染物会议上,单端孢霉烯族毒素被定为最危险的自然发生食品污染物。列入国际研究的优先地位。在我国对DON毒素的研究兴趣曾与食道癌的发生有关,最近,有人曾调查大骨节病区粮食中DON毒素的分布情况,亦看出有一定的规律性。本文对这一族毒素之一的DON毒素近年来的研究概况综述如下。
Deoxynivalenol (DIN), one of the trichothecenes, is widespread in nature. It is currently considered as one of the major natural toxins present in the wheat head blight. It can cause human and animal poisoning. Although it is less toxic than other mycotoxins of the same ethnic group, it is a great hazard to human beings and animals because of its widespread presence and large-scale contamination of food. Trichothecene toxins were identified as the most dangerous naturally occurring food contaminants at the third meeting of the Food Additives and Contaminants jointly organized by the UN Food and Agriculture Organization and the World Health Organization in 1973. Be included in the priority of international research. In our country, the research interest of DON toxins has been related to the occurrence of esophageal cancer. Recently, some people have investigated the distribution of DON toxins in grains in patients with Kashin-Beck disease and also found some regularity. In this paper, DON toxin of this group of toxins in recent years, a summary of the research are summarized below.