论文部分内容阅读
化学物质的作用不仅与其剂量有关,也与该物质在受影响的器官内存在的时间有关。物质在主要受危害器官中减少到一半所经过的时间叫半减期(T)。一昼夜内,物质的排出量对其含量的百分比叫排泄率(Q)。T与Q的关系;Q=100(1-e~(-0.698/T)%。显然,T值越大,物质的蓄积作用越强。因此,T与Q是定量评价化学物质蓄积特性的客观指标。如果T=1
The effect of a chemical substance depends not only on its dosage but also on how long the substance is present in the affected organ. The time elapsed between a substance being reduced to half of the major harmed organ is called a half-life (T). Within a day and night, the percentage of substance excreted to its content is the rate of excretion (Q). T and Q; Q = 100 (1-e ~ (-0.698 / T)%. Obviously, the larger the value of T, the stronger the accumulation of matter.Therefore, T and Q are objective quantitative evaluation of the accumulation characteristics of chemical substances Indicator. If T = 1