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目的:探讨连续血液净化(CBP)辅助治疗对急性肾功能衰竭(ARF)伴多器官功能障碍综合征(MODS)的预后影响。方法:回顾性分析我院2009年10月至2011年10月收治的应用连续血液净化(CBP)治疗ARF伴MODS 26例的临床资料。结果:CBP治疗后血尿毒素、K~+、pH值、HCO_3~-、BE、AST、LDH、乳酸、MAP、CVP、HR、PO_2/FiO_2、APACHEⅡ均较治疗前显著改善,P均<0.05;30 d、60 d生存率分别为68.2%和59.1%。结论:CBP能纠正电解质、酸碱失衡,改善内环境和器官功能,最终改善预后。
Objective: To investigate the effect of continuous blood purification (CBP) adjuvant therapy on the prognosis of acute renal failure (ARF) with multiple organ dysfunction syndrome (MODS). Methods: A retrospective analysis of our hospital from October 2009 to October 2011 admitted to the application of continuous blood purification (CBP) treatment of ARF with MODS in 26 cases of clinical data. Results: Compared with those before treatment, CBP treatment significantly improved the blood urea nitrogen, K +, pH, HCO 3 -, BE, AST, LDH, lactate, MAP, CVP, HR, PO 2 / FiO 2 and APACHE Ⅱ The 30-day and 60-day survival rates were 68.2% and 59.1% respectively. Conclusion: CBP can correct the electrolyte, acid-base imbalance, improve the internal environment and organ function, and ultimately improve the prognosis.