目的:探讨机器人辅助全髋关节置换术（total hip arthroplasty, THA）治疗股骨头坏死的近期临床疗效。方法:回顾性分析2018年8至12月因股骨头坏死行MAKO机器人辅助THA的患者23例32髋（MAKO THA组），随机抽取相同时间段因相同诊断行常规THA的患者23例32髋（常规THA组）。两组患者性别、侧别、年龄、身高、体重、体质指数、国际骨循环研究协会（Association Research Circulation Osseous, ARCO）分期、术前Harris髋关节评分、西安大略和麦克马斯特大学（Western Ontario and McMaster Universities，WOMAC）骨关节炎指数、下肢长度差的差异均无统计学意义。MAKO THA组在机械臂的辅助下进行髋臼侧磨削和假体安装，在MAKO系统的反馈下行下肢长度及偏心距调整，其余术中操作与术后处理同常规THA组。比较两组手术时间、并发症发生率、术后影像学参数（外展角、前倾角、下肢长度差、偏心距差），MAKO手术计划与术后X线片髋臼假体位置的一致性，MAKO手术计划与术后CT髋臼假体外展角和前倾角的一致性，术后Harris髋关节评分、WOMAC指数及遗忘关节评分。结果:MAKO THA组手术时间为（101.2±19.9）min，较常规THA组的（65.5±5.6）min延长（n t=7.659，n P<0.001）；髋臼假体前倾角为22.63°±5.58°，大于常规THA组的15.98°±7.13°（n t=4.156，n P<0.001）；下肢长度差为（0.35±0.30）cm，小于常规THA组的（0.87±0.43）cm（n t=4.775，n P<0.001）；偏心距差为（0.27±0.19）cm，小于常规THA组的（0.49±0.16）cm（n t=4.155，n P<0.001）。两组外展角（41.59°±4.04°，42.72°±4.45°）的差异无统计学意义（n t=1.026，n P=0.292）。MAKO手术计划与术后髋臼假体外展角的差异为1.18°±2.52°，前倾角的差异为2.06°±2.79°，一致性好（n r=0.846, 0.810；n P<0.001）；关节旋转中心在水平方向和垂直方向上的差异分别为（2.25±1.08）mm和（2.20±1.28）mm，一致性好（n r=0.975，0.974；n P0.05）。MAKO THA组与常规THA组术后12个月Harris髋关节功能评分改善值分别为（39.7±6.01）分和（40.2±5.57）分，差异无统计学意义（n t=0.364，n P=0.717）；WOMAC指数改善值分别为（54.7±11.68）分和（55.6±9.22）分，差异无统计学意义（n t=0.344，n P=0.732）。MAKO THA组4髋出现髂前上棘钉孔一过性渗血，无其他术中及术后并发症。n 结论:MAKO机器人辅助THA较常规手术更加精准和稳定，前倾角更接近20°的目标，下肢长度差和髋关节偏心距差更小，术后早期临床疗效相同，但手术时间相应延长。“,”Objective:To explore the radiology and short-term clinical outcomes of MAKO robotic-assisted total hip arthroplasty (THA).Methods:The present study retrospectively reviewed the medical records of 23 patients (32 hips) who diagnosed as osteonecrosis of the femoral head and underwent MAKO THA from August 1st to December 31st, 2018 as MAKO THA group. A total of 23 patients (32 hips) with the same diagnosis underwent manual THA at the same time as conventional THA group. There was no statistical difference between the two groups in terms of gender, affected side, age, height, weight, Body Mass Index (BMI), stage of the Association Research Circulation Osseous (ARCO), preoperative Harris hip score, WOMAC Osteoarthritis Index and limb length discrepancy. The patients in both groups were operated by the same doctors. The MAKO THA group underwent the acetabular preparation and the acetabular shell impaction with the assistance of the robotic arm. The leg length and offset were adjusted under the feedback of the MAKO system. Other intraoperative procedures and postoperative interventions of MAKO THA group were similar as conventional THA group. The operation duration, incidence of complications, the radiograph parameters (version, leg length discrepancy and offset), consistency of acetabular prosthesis position in MAKO operation plan, position in postoperative X-ray, the consistency of acetabular prosthesis inclination, version in MAKO operation plan, angles in postoperative CT and functional scores (Harris hip score, WOMAC Osteoarthritis Index and forgotten joint score) at 6 months and 12 months after operation were compared between the two groups.Results:The operation duration of the MAKO THA group was longer than that of the conventional THA group (101.2±19.9 min, 65.5±5.6 min, n t=7.659, n P<0.001). In terms of radiograph parameters, the different of version (22.63°±5.58°, 15.98°±7.13°,n t=4.156, n P<0.001) and limb length discrepancy (0.35±0.30 cm, 0.87±0.43 cm,n t=4.775, n P<0.001) and offset (0.27±0.19 cm, 0.49±0.16 cm,n t=4.155, n P<0.001) between the two groups were statistically significant. The MAKO operative plan and postoperative radiographs were measured. The difference of inclination/version were 1.18°±2.52°/2.06°±2.79° (n r=0.846, n P<0.001;n r=0.810, n P<0.001), respectively. The horizontal/vertical directions of the joint rotation center were 2.25±1.08 mm and 2.20±1.28 mm (n r=0.975, n P<0.001;n r=0.974, n P<0.001), respectively. In terms of functional results at 6 months and 12 months after operation, Harris hip score in MAKO THA group and in conventional THA group was 90.2±5.40/89.9±5.23 (n t=0.188, n P=0.851) and 93.9±2.31/94.0±2.61 (n t=0.254, n P=0.801), respectively. The WOMAC index was 27.3±10.36/29.1±12.03 (n t=0.623, n P=0.535) and 16.4±8.39/15.2±8.35 (n t=0.597, n P=0.552). The forgotten joint score was 76.3±6.11/73.7±6.84 (n t=1.560, n P=0.124) and 81.7±4.52/80.7±5.11 (n t=0.816, n P=0.418), respectively. Transient bleeding in the anterior superior iliac spine pin holes were reported in 4 hips after discharge in MAKO THA group, which were healed after dressing change. No other intraoperative or postoperative complication was reported.n Conclusion:Robotic-assisted THA were more accurate and stable than conventional THA. The version of robot-assisted THA was closer to the target of 20° with similar discrepancy in leg length and hip offset. The short-term functional outcomes were similar in the two groups. However, the operation duration of robot-assisted THA was prolonged.