论文部分内容阅读
目的 对原发性肝癌患者行介入性化疗栓塞进行风险预测。方法 将 1 1 6例行介入栓塞治疗的原发性肝癌患者根据术后的肝功能分为良好组、轻度损害组、重度损害组 ,对 3组病例之间术前的肝功能和储备功能进行单因素分析 (秩和检验 )和多因素分析 (有序多项分类Logistic回归 ) ,对肝癌患者行介入性化疗栓塞后的肝功能损害进行预测。结果 3组之间术前丙氨酸转氨酶、天冬氨酸转氨酶、γ 谷氨酰转肽酶、碱性磷酸酶差异均无显著性意义 (P >0 0 5) ,而吲哚靛青绿负荷实验1 5min潴留率和Child分级差异有显著性意义 (P <0 0 5) ,Logicits回归推导出 3个预测术后分组的方程式 ,实际符合率为 82 76 %。结论 ICGR1 5和Child分级是评估行介入栓塞治疗肝癌患者的肝储备功能的较好的指标 ,预测方程为肝癌的介入栓塞治疗提供了 1个安全评估依据
Objective To predict the risk of interventional chemoembolization in patients with primary liver cancer. Methods One hundred and sixteen patients with primary liver cancer undergoing interventional embolization were divided into two groups based on postoperative liver function: good group, mild damage group and severe injury group. The preoperative liver function and reserve function Univariate analysis (rank sum test) and multivariate analysis (ordered multinomial Logistic regression) were used to predict the liver damage after interventional chemoembolization in patients with liver cancer. Results There was no significant difference in the levels of alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase and alkaline phosphatase between the three groups before operation (P> 0.05), while indocyanine green load There was a significant difference between the retention rate and Child classification (P <0.05) at 15 minutes after the experiment. Logicits regression derived three equations predicting the postoperative grouping, the actual compliance rate was 82.76%. Conclusion ICGR1 5 and Child classification is a good indicator to evaluate the hepatic reserve function in patients with hepatic carcinoma after interventional embolization. The prediction equation provides a safety assessment basis for the interventional embolization of liver cancer