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目的探讨染料法识别宫颈癌前哨淋巴结(SLN)活检时出现假阴性的原因。方法选择49例早期宫颈癌患者,术前宫颈瘤周注射亚甲蓝,行广泛子宫切除+盆腔淋巴结清扫术;进行前哨淋巴结定位及病理学检查。结果SLN识别率为87.8%(43/49),灵敏度为81.8%,准确率为92%,假阴性率为18.2%。结论本组假阴性与肿瘤大小、淋巴转移的途径、术前放疗、病理检测方法有关。
Objective To investigate the causes of false negatives in the identification of sentinel lymph node (SLN) biopsy in cervical cancer by dye method. Methods 49 patients with early stage cervical cancer were selected. Methylene blue was injected into the perineurium before operation, extensive hysterectomy and pelvic lymphadenectomy were performed, and sentinel lymph node localization and pathological examination were performed. Results The recognition rate of SLN was 87.8% (43/49), the sensitivity was 81.8%, the accuracy rate was 92% and the false negative rate was 18.2%. Conclusion This group of false negative and tumor size, lymphatic metastasis, preoperative radiotherapy, pathological detection methods.