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目的了解青海省藏区育龄妇女弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒和其他有关病毒(简称为TORCH)感染因素。方法 2013年5月采集550份藏族育龄妇女血清标本进行TORCH检测,同时采用问卷收集TORCH感染的相关因素,使用t检验和χ~2检验单因素和多因素logistic分析方法,对可能影响藏族育龄妇女TORCH感染的因素进行筛选。结果 550名藏区藏族育龄妇女TORCH阳性率HSVⅡ-Ig M为15.82%(87/550),Toxo-Ig M为0.91%(5/550)。单因素分析TORCH感染与文化程度、收入水平、有无配偶、初次性生活年龄、有无性伴侣、有无异常妊娠史、准备怀孕阶段行为及孕期接触动物行为均有统计学差异(P<0.05)。多因素logistic分析表明,文化程度(OR=11.24,95%CI=5.81~21.74)、初次性生活年龄(OR=3.54,95%CI=1.323~9.448)、月收入水平(OR=0.517,95%CI=0.301~0.886)、有无性伴侣(OR=0.051,95%CI=0.028~0.091)、异常妊娠史(OR=0.173,95%CI=0.065~0.464)是感染TORCH的影响因素。结论文化程度、收入水平、初次性生活年龄、异常妊娠史是导致藏区育龄妇女TORCH高感染率的重要影响因素。
Objective To understand the infection factors of Toxoplasma gondii, rubella virus, cytomegalovirus, herpes simplex virus and other related viruses (TORCH) in women of childbearing age in Qinghai Province. Methods A total of 550 Tibetan women of childbearing age were collected for TORCH detection in May 2013. At the same time, questionnaires were used to collect the relevant factors of TORCH infection. The t-test and χ ~ 2 test were used to test the correlation between TORCH and Tibetan women of childbearing age TORCH infection factors to be screened. Results The positive rates of TORCH in Tibetan women of reproductive age in Tibetan areas were 15.82% (87/550) and 0.91% (5/550) for HSVⅡ-IgM. Univariate analysis showed significant difference (P <0.05) between TORCH infection and educational level, income level, spouse with or without spouse, age of first sex, sexual partner with or without abnormal pregnancy history, behavior during preparation for pregnancy and contact animal during pregnancy . Multivariate logistic analysis showed that the educational level (OR = 11.24, 95% CI = 5.81-21.74), the age of first-time sexual life (OR = 3.54, 95% CI = 1.323-9.448), monthly income (OR = 0.517, 95% CI = 0.301 ~ 0.886). There was no sexual partner (OR = 0.051, 95% CI = 0.028-0.091). The abnormal pregnancy history (OR = 0.173, 95% CI = 0.065-0.464) was the influencing factor of TORCH infection. Conclusion The educational level, income level, the age of first sexual life and the history of abnormal pregnancy are the important factors that lead to the high infection rate of TORCH in women of childbearing age in Tibetan area.