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目的:分析严重多发伤患者感染病原菌的分布及耐药性。方法:自2007年4月-2011年2月间我院收治的428例严重多发伤患者中分离出病原菌,分析其种类分布以及耐药率。结果:共分离病原菌436株,G-菌占59.4%,主要为铜绿假单胞菌、鲍蔓氏不动杆菌,大肠埃希菌;G+菌占40.6%,主要为凝固酶阴性葡萄球菌、金黄色葡萄球菌。肠球菌属和肺炎链球菌属。严重多发伤患者感染病原菌对抗生素的耐药问题严重,且程度不同。结论:严重多发伤患者感染源主要为G-杆菌,病原菌耐药严重,且程度不一,临床中应合理选用针对性的抗生素。
Objective: To analyze the distribution and drug resistance of pathogenic bacteria in patients with severe multiple trauma. Methods: From April 2007 to February 2011 in our hospital 428 cases of severe traumatic injury isolated from pathogens, analysis of their species distribution and resistance rates. Results: A total of 436 pathogenic bacteria were isolated, accounting for 59.4% of G-bacteria, mainly Pseudomonas aeruginosa, Acinetobacter baumannii and Escherichia coli; G + bacteria accounted for 40.6%, mainly coagulase-negative Staphylococcus aureus, gold Staphylococcus aureus. Enterococcus and Streptococcus pneumoniae. Serious multi-traumatic patients infected with pathogens resistance to antibiotics serious, and to varying degrees. CONCLUSIONS: The main source of infection in patients with severe multiple trauma is G-bacilli. The pathogens are severely drug-resistant and have varying degrees of severity. In clinical practice, targeted antibiotics should be rationally selected.