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为了观察肠安泰胶囊对肠管粘膜免疫系统T细胞及NK细胞的诱导 ,建立了大肠癌肺转移小鼠动物模型 ,采用ABC免疫染色方法对小肠 ,大肠免疫因素做相关分析。结果显示荷瘤对照组与正常对照组相比 ,T细胞及NK细胞在小肠 ,大肠均有增加趋势。荷瘤治疗组与荷瘤对照组相比 ,T细胞及NK细胞在小肠有显著性增加 (P <0 0 1)。提示肠安泰胶囊预防大肠癌肺转移的机理 ,与其诱导肠管粘膜免疫系统T细胞及NK细胞有关
In order to observe the induction of intestinal mucosal immune system T cells and NK cells by Chang’an Capsule, an animal model of colorectal cancer lung metastasis was established. The ABC immunostaining method was used to analyze the intestinal and colonic immune factors. The results showed that compared with the normal control group, the T-cell and NK cells in the tumor-bearing control group increased in the small intestine and large intestine. In the tumor-bearing treatment group, T cells and NK cells were significantly increased in the small intestine compared with the tumor-bearing control group (P < 0 01). Suggests that Changantai Capsule can prevent the lung metastasis of colorectal cancer, and it is related to the induction of intestinal mucosal immune system T cells and NK cells