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在碳酸钾、丙酮的水溶液中由N-酰基四氢噻唑-2-硫酮进行氨基酸解得到10种N-酰基-α-氨基酸Ⅰ_a-(?)发现在三聚氯氰及三乙胺存在下,由N-酰基-α-氨基酸环合成8种饱和5(4H)-(口恶)唑酮Ⅱ_a-h的新方法,进而在硫酸铁催化下得到10种不饱和5(4H)-(口恶)唑酮衍生物Ⅲ_a-(?)
Amino acid hydrolysis of N-acyltetrahydrothiazole-2-thiones in aqueous potassium carbonate and acetone gave 10 N-acyl-a-amino acids I-a (?) Found in the presence of cyanuric chloride and triethylamine , A new method of ring-opening N-acyl-α-amino acids into 8 kinds of saturated 5 (4H) - oxazolidinone Ⅱ_a-h was obtained. E) oxazolone derivatives III_a- (?)