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目的探讨血液透析患者睡眠障碍与心包脏层脂肪组织(EAT)体积的潜在关系。方法选择透析时间超过3个月且病情比较稳定的维持性血液透析(MHD)患者82例,根据匹兹堡睡眠质量量表(PSQI)积分分为两组,睡眠障碍组(PQSI>5分)和对照组(PQSI≤5分)。观察两组PQSI、爱泼沃思嗜睡量表(ESS)、心包脏层脂肪的体积,并探讨血液透析患者睡眠质量与心包脏层脂肪的体积的相关性。结果两组患者性别和年龄均差异无统计学意义(P>0.05),但睡眠障碍组患者CRP,瘦素较对照组更高,差异有统计学意义。睡眠障碍组EAT体积(170.0±17.0)cm3,对照组EAT体积(141.9±22.4)cm3,两组EAT差异有统计学意义(P<0.05)。结论维持性血液透析患者发生睡眠质量与EAT体积的改变存在相关关系。
Objective To investigate the potential relationship between sleep disorders and the volume of pericardial fat tissue (EAT) in hemodialysis patients. Methods Eighty-two patients with maintenance hemodialysis (MHD) who had been on dialysis for more than 3 months and had stable disease were divided into two groups according to Pittsburgh Sleep Quality Scale (PSQI), sleep disturbance group (PQSI> 5) and control Group (PQSI ≤ 5 points). The volumes of PQSI, Epsom Sleepiness Scale (ESS), and pericardial fat in the two groups were observed, and the correlation between sleep quality and the volume of pericardial fat in hemodialysis patients was also investigated. Results There was no significant difference in gender and age between the two groups (P> 0.05). However, the CRP and leptin levels in the sleep disorder group were higher than those in the control group, and the difference was statistically significant. The EAT volume was (170.0 ± 17.0) cm3 in the sleep disorder group and 141.9 ± 22.4 cm3 in the control group, and there was significant difference between the two groups (P <0.05). Conclusion There is a correlation between sleep quality and volume of EAT in maintenance hemodialysis patients.