右泪囊角化型基底细胞癌一例报告

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患者,男,29岁。右眼溢泪4~5年。近1年来伴有脓性分泌物自右下泪点溢出。内眦沮囊部位软组织渐渐隆起。于1991年11月19日收入住院。眼部检查:视力右1.5,左1.5,右眼内眦部相当于泪囊处隆起约3 mm,边界不清,质软,挤压有少量粘脓自下泪点溢出,挤压后肿块不消失,泪道冲洗通而不畅,明显狭窄,X线摄片无骨质破坏。于同年11月23日在局麻下行右眼泪囊探查术。切开泪囊前膜,见泪囊内充满颗粒状,表面呈乳头状新生物,经分离完整摘除泪囊见肿物完全从泪囊内翻出,呈菜花样,暗红色,约2×1.5×1 cm大小。病理检查:肿块系肿瘤组织,瘤细胞同基底细胞的形态,但具有异型性,排例成实性团块状,在其周围有单层柱状上皮细胞作栅状排例,小区在瘤细胞团中央有角化现象。病理诊断:右泪囊角化型基底细胞癌。讨论泪囊基底细胞癌在临床上极为少见。基底细胞上皮癌,可原发性,也可由乳头状瘤转变 Patient, male, 29 years old. Right eye tears 4 to 5 years. In the past 1 year, purulent secretions have overflowed from the lower right tear point. The soft tissue of the internal hemorrhoids gradually bulges. He was admitted to hospital on November 19, 1991. Eye examination: visual acuity right 1.5, left 1.5, the right eye internal malleolus is equivalent to about 3 mm bulge at the lacrimal sac Department, the border is unclear, soft, there is a small amount of sticky pus squeezed from the bottom of the tear point, the swelling is not Disappeared, the lacrimal passages were flush and obstructed, and they were obviously narrow. The X-rays showed no bone destruction. On the 23rd of the same year, the right lacrimal cyst was examined under local anesthesia. Cut open the lacrimal sac membrane, see the lacrimal sac filled with granules, the surface is a papillary new organism, after the complete removal of the lacrimal sac, see the tumor completely out of the lacrimal sac, cauliflower, dark red, about 2 × 1.5 ×1 cm size. Pathological examination: Tumor is a tumor tissue, the morphology of the tumor cell is the same as that of the basal cell, but it has atypicality, and it is arranged as a solid mass. There is a single layer of columnar epithelial cells arranged in a grid pattern, and the cell is in the tumor cell group. The central phenomenon is keratinization. Pathological diagnosis: right lacrimal keratocytic basal cell carcinoma. Discussion Lacrimal squamous cell carcinoma is extremely rare in the clinic. Basal cell epithelial cancer, primary, may also be transformed by papilloma
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