多房棘球绦虫的中绦期所致泡球蚴病的发病机制涉及泡球蚴与宿主的相互作用,包括局部和全身的作用。在泡球蚴的各种产物与特异性和非特异性细胞免疫反应之间,有复杂的信号分子介导,这是引起占位性病变显著病理变化的原因。本文就泡球蚴病实验研究的结果和临床病理表现之间的关系作一综述,以阐明发病机制的某些环节。 The pathogenesis of alveolar echinococcosis caused by midgard period of Echinococcus multilocularis involves the interaction of metacercariae with the host, including both local and systemic effects. Between the various products of Echinococcus granulosus and specificity and nonspecific cellular immune response, there are complex signal molecules mediated, which is responsible for the significant pathological changes caused by space-occupying lesions. This article summarizes the results of the experimental study of alveolar echinococcosis and clinicopathological findings to elucidate some aspects of the pathogenesis.