动脉粥样硬化(AS)是心脑血管疾病的主要病理学基础,由多因素诱导的复杂病变。在其众多的致病因素中,氧化损伤与AS的发生发展密切相关。因此针对AS氧化损伤途径进行抗氧化被认为是有效预防和治疗AS的方法之一。在抗氧化酶家族中,超氧化物歧化酶(SOD)在抗氧化损伤方面发挥着重要的作用,本文对近年来SOD抗氧化损伤与AS之间关系的研究作一综述。 Atherosclerosis (AS) is the main pathological basis of cardiovascular and cerebrovascular diseases, complicated by multiple factors induced lesions. Among its many pathogenic factors, oxidative damage is closely related to the occurrence and development of AS. Therefore, the anti-oxidation of AS oxidative damage pathway is considered as one of the effective ways to prevent and treat AS. In the antioxidant enzyme family, superoxide dismutase (SOD) plays an important role in the anti-oxidative injury. In this paper, we reviewed the recent progress in the study of the relationship between antioxidant enzymes and AS.