论文部分内容阅读
青少年特发性脊柱侧凸(adolescent idiopathic scoliosis,AIS)是青春前期或骨骼成熟前发生的脊柱侧凸,至今病因不明,是脊柱侧凸中最常见的类型,约占结构性侧凸的75%~80%[1]。AIS的发病原因,目前仍在深入研究之中,但大量的临床观察和实验研究资料表明,许多因素与AIS的发病有着密切的关系。现代医学研究,从流行病学调查及实验研究资料中证实,AIS病因可能与以下几个方面有关:遗传因素;神经系统因素;躯干生长不平衡及内分泌异常等。目前AIS总的治疗原则是早期发现、早期治疗、适时手术矫正、防止侧凸继续进展。本文就AIS发病原因及其治疗的最新研究进展论述如下。
Adolescent idiopathic scoliosis (AIS) is a scoliosis that occurs prior to pre-puberty or skeletal maturation. To date, the etiology is unknown and is the most common type of scoliosis, accounting for about 75% of structural scoliosis ~ 80% [1]. The pathogenesis of AIS, is still under study, but a large number of clinical observations and experimental studies show that many factors have a close relationship with the incidence of AIS. Modern medical research, from epidemiological investigations and experimental studies confirmed that the aetiology of AIS may be related to the following aspects: genetic factors; nervous system factors; trunk growth imbalance and endocrine disorders. The current AIS general treatment principle is early detection, early treatment, timely surgical correction, to prevent the progression of scoliosis. This article on the causes of AIS and its treatment of the latest research progress is discussed below.