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慢性心力衰竭（CHF）是心血管疾病主要的死亡原因。可溶性 ST2（sST2）作为一种新的心脏标志物，与CHF存在相关性。 ST2是炎性因子白细胞介素1受体家族的成员之一，是由过负荷的心肌细胞分泌的血清蛋白。 CHF患者血清 sST2水平升高，且与心力衰竭严重程度、左心室射血分数、脑钠肽等相关，对鉴别不同程度心力衰竭及其预后评估有一定临床意义，是独立预测心力衰竭患者短期病死率的强力指标。“,”Chronic heart failure ( CHF) is a major cause of death from cardiovascular disease.Soluble ST2 ( sST2) as a new cardiac marker,has a correlation with CHF.ST2 is one of the interleukin-1 receptor family members of inflammatory factors,a serum protein secreted by the overloaded myocardial cells.CHF patients′sST2 levels are elevated,and are associated with the severity of heart failure,left ventricular ejection fraction,creatinine clearance,brain natriuretic peptide,which has a certain clinical significance for assessing different degrees of heart failure and its prognosis,and is an independent strong predictor of short-term mor-tality in patients with heart failure .